منابع مشابه
De novo sirolimus with low-dose tacrolimus versus full-dose tacrolimus with mycophenolate mofetil after heart transplantation--8-year results.
BACKGROUND Although acute cellular rejection after heart transplantation (HTX) can be controlled by full-dose calcineurin inhibitor (CNI)-based immunosuppressive regimens, cardiac allograft vasculopathy (CAV), nephrotoxicity, and malignancy remain ongoing problems. To evaluate the potential beneficial effects of sirolimus and CNI reduction, we compared de novo low-dose tacrolimus and sirolimus ...
متن کاملTacrolimus in renal transplantation.
The early studies with tacrolimus. from 1989 through 1991, included a pilot series, a small randomized trial, and a larger nonrandomized group. I.3.4 When the outcome of these patients was compared with that in a roughly concurrent (although somewhat less challenging) group of cyclosporine (CyA)-treated patients, equivalent patient and graft survival rates were seen. However, improved secondary...
متن کاملTopical Tacrolimus for Psoriasis
Tacrolimus ointment is an agent approved for the treatment of atopic dermatitis; however, tacrolimus has been expected also as one of the promising therapeutic strategies for other T-cell mediated inflammatory skin disorders. Recent progress have demonstrated that topical tacrolimus shows beneficial effects for psoriasis depending on sites. In particular, facial, intertriginous, and genital pso...
متن کاملClinical Pharmacokinetics of Tacrolimus in Iranian Liver Transplant Recipients
Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...
متن کامل[Topical tacrolimus-induced lentigines].
Varón de 11 años de raza caucásica y fototipo II con dermatitis atópica, que presenta desde hace 2 meses múltiples lesiones maculosas hiperpigmentadas de 1-2 mm de diámetro en huecos antecubitales (fig. 1). La dermatoscopia muestra retículo pigmentado delicado y zonas con glóbulos marrones (fig. 2). Durante los 8 meses previos a la consulta el paciente aplicó, sin realizar fotoprotección solar,...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2011
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.100.2948